Center for Addiction Medicine

The Effect of Cannabis on Cognition and Neuroimaging in those with Major Depressive Disorder

The prevalence of use of MJ among those with Major Depressive Disorder (MDD) is unknown, but MDD is the third most common reason for individuals to seek medical MJ, after pain and insomnia. It is therefore of critical importance to understand the effects of MJ use and MDD on brain function, particularly in young adults. In this neuroimaging study, we investigated the neural correlates of emotion processing and neural activity in those with and without MDD and MJ use.