Center for Addiction Medicine


Much of the important research at the Center for Addiction Medicine has been published in journals. To appreciate the full range of work by Center members, please explore the links next to the names below. We’ve also listed some of our important pieces in the Highlights area, organized into the following categories: Marijuana Use, Tobacco Use, Alcohol Studies, and Research Methodology.

A. Eden Evins, M.D., M.P.H. | Search
John F. Kelly, Ph.D. | Search
Cori Cather, Ph.D. | Search
Paola Pedrelli, Ph.D. | Search
Bettina Hoeppner, Ph.D. | Search
Gladys Pachas, M.D. | Search
Melissa Culhane Maravic, Ph.D, M.P.H.| Search
Jodi Gilman, Ph.D. | Search
Brandon G. Bergman, Ph.D. | Search
Randi Schuster, Ph.D. | Search
Hasan Onur Keles, PhD. | Search
Corrie L. Vilsaint, Ph.D. | Search
David Eddie, Ph.D. | Search

Some Highlights


Altered neural processing to social exclusion in young adult marijuana users
JM Gilman, MT Curran, V Calderon, RM Schuster, AE Evins
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Cannabis use is quantitatively associated with nucleus accumbens and amygdala
abnormalities in young adult recreational users
JM Gilman, JK Kuster, S Lee, MJ Lee, BW Kim, N Makris, …
The Journal of Neuroscience 34 (16), 5529-5538

Young adult cannabis users report greater propensity for risk-taking only in non-monetary domains
JM Gilman, V Calderon, MT Curran, AE Evins
Drug and alcohol dependence 147, 26-31

Does Cannabis Cause, Exacerbate or Ameliorate Psychiatric Disorders;
An Oversimplified Debate Discussed

M Haney, AE Evins
Neuropsychopharmacology 41 (2), 393-401

The Prevalence of Cannabis Withdrawal and Its Influence on Adolescents’ Treatment
Response and Outcomes: A 12-Month Prospective Investigation.
Greene CM, Kelly JF.
Journal of addiction medicine. 2014;8(5):359-367.


Lower gray matter density and functional connectivity in the anterior insula
in smokers compared with never smokers
LE Stoeckel, XJ Chai, J Zhang, S Whitfield‐Gabrieli, AE Evins
Addiction biology

Brain reactivity to smoking cues prior to smoking cessation predicts
ability to maintain tobacco abstinence
AC Janes, DA Pizzagalli, S Richardt, S Chuzi, G Pachas, MA Culhane, …
Biological psychiatry 67 (8), 722-729

The effects of transdermal nicotine on cognition in nonsmokers with
and nonpsychiatric controls
RS Barr, MA Culhane, LE Jubelt, RS Mufti, MA Dyer, AP Weiss, …
Neuropsychopharmacology 33 (3), 480-490

Medical morbidity and mortality in schizophrenia: guidelines for psychiatrists.
DC Goff, C Cather, AE Evins, DC Henderson, O Freudenreich, …
Journal of Clinical Psychiatry

Maintenance treatment with varenicline for smoking cessation in patients with
schizophrenia and bipolar disorder: a randomized clinical trial
AE Evins, C Cather, SA Pratt, GN Pachas, SS Hoeppner, DC Goff, …
Jama 311 (2), 145-154


Why we like to drink: a functional magnetic resonance imaging study
of the rewarding and anxiolytic effects of alcohol
JM Gilman, VA Ramchandani, MB Davis, JM Bjork, DW Hommer
The Journal of Neuroscience 28 (18), 4583-4591

Subjective and neural responses to intravenous alcohol in young adults
with light and heavy drinking patterns
JM Gilman, VA Ramchandani, T Crouss, DW Hommer
Neuropsychopharmacology 37 (2), 467-477

Young Adults, Social Networks, and Addiction Recovery: Post Treatment Changes
in Social Ties and Their Role as a Mediator of 12-Step Participation.
Kelly JF, Stout RL, Greene CM, Slaymaker V.
PloS onePloS one. 2014;9:e100121.

Does Alcoholics Anonymous work differently for men and women?
A moderated multiple-mediation analysis in a large clinical sample.
Kelly JF, Hoeppner BB.
Drug and alcohol dependence. 2013;130(1):186-193.

Determining the relative importance of the mechanisms of behavior change
within Alcoholics Anonymous: a multiple mediator analysis.
Kelly JF, Hoeppner B, Stout RL, Pagano M.
AddictionAddiction. 2012;107:289-99.Abstract


Detecting treatment‐covariate interactions using permutation methods
R Wang, DA Schoenfeld, B Hoeppner, AE Evins
Statistics in medicine 34 (12), 2035-2047

The problem of the placebo response in clinical trials for psychiatric disorders:
culprits, possible remedies, and a novel study design approach
M Fava, AE Evins, DJ Dorer, DA Schoenfeld
Psychotherapy and psychosomatics 72 (3), 115-127

Impulsive social influence increases impulsive choices on a temporal
discounting task in young adults
JM Gilman, MT Curran, V Calderon, LE Stoeckel, AE Evins
PloS one 9 (7), e101570

Single dose of a dopamine agonist impairs reinforcement learning in humans:
behavioral evidence from a laboratory-based measure of reward responsiveness
DA Pizzagalli, AE Evins, EC Schetter, MJ Frank, PE Pajtas, DL Santesso, …
Psychopharmacology 196 (2), 221-232

Optimizing real time fMRI neurofeedback for therapeutic discovery and development
LE Stoeckel, KA Garrison, SS Ghosh, P Wighton, CA Hanlon, JM Gilman, …
NeuroImage: Clinical 5, 245-255

A controlled trial of bupropion added to nicotine patch and behavioral therapy for
smoking cessation in adults with unipolar depressive disorders
AE Evins, MA Culhane, JE Alpert, J Pava, BS Liese, A Farabaugh, M Fava
Journal of clinical psychopharmacology 28 (6), 660

Varenicline for smoking cessation in schizophrenia:
safety and effectiveness in a 12-week open-label trial
GN Pachas, C Cather, SI Pratt, B Hoeppner, J Nino, SV Carlini, …
Journal of dual diagnosis 8 (2), 117-125

Opioid antagonists for smoking cessation
SP David, T Lancaster, LF Stead, AE Evins, JJ Prochaska
Cochrane Database Syst Rev 6

Does using marijuana increase the risk for developing schizophrenia
AE Evins, AI Green, JM Kane, RM Murray
J Clin Psychiatry 74 (4), e08

Reassessing the safety of varenicline
AE Evins
American Journal of Psychiatry