Center for Addiction Medicine

Participate in a Study

Clinical research is at the heart of all medical advances. At the MGH Center for Addiction Medicine, we aim to develop new and effective treatments for drug use disorders and to understand the effects of drug use on the brain and body. It is your participation that helps researchers to ultimately uncover better ways to treat and prevent drug use disorders and to understand the effects of drugs on the brain. We have the highest standards for protection of the confidentiality and privacy of all study participants at the MGH-CAM.

Visit the National Institute of Health’s web site for more information on clinical research trials. Learn about what this kind of study is, why people participate, and what the experience was like for both volunteers and researchers.

Studies at MGH-CAM seeking volunteers

To inquire about participating, please see the list below, organized by category. Use the contact information provided for the study in which you’re interested.



Studies in people who use marijuana regularly

Using Imaging to Assess Effects of THC on Brain Activity, PI: Jodi Gilman, Ph.D. The purpose of this study is to assess the effects of THC intoxication on the brain by using the FDA-approved medication dronabinol (synthetic THC). Participants complete one 6-hour study visit. You must be between the ages of 18-55 and use marijuana to participate.
Visit or call (617) 643-4689 to see if eligible.


Studies in medical marijuana

Effect of Medical Marijuana on Neurocognition and Escalation of Use, PI: Jodi Gilman, Ph.D. The purpose of the study is to help us learn about peoples’ behavior once they start using medical marijuana (MM). We hope to better understand patterns of use of medical marijuana, as well as any effects of medical marijuana on cognition or on the brain, including the potential for marijuana dependence/addiction.
Visit or call (617) 643-7611 to see if eligible.


Studies in adolescents who do or do not use marijuana

Adolescent Cognition and Health, PI: Randi Schuster, Ph.D. The purpose of this study is to understand how cognition may change when adolescents (ages 13-19) stop using marijuana. The project aims to understand how (or if) marijuana influences one’s thinking abilities..
Visit or call (617) 643-3575 to see if eligible.


Studies in people who have experienced trauma and do or do not use marijuana

Decision-Making and Drug Use, PI: Jodi Gilman, Ph.D. The purpose of this study is to better understand the brain circuitry and emotions in adults (ages 18-55) who have experienced a traumatic event. This study involves cognitive testing and magnetic resonance imaging (MRI) scans to better understand behavior and brain regions that may be affected by MDD.
Visit or call (617) 643-4692 to see if eligible.



Reduced Nicotine Cigarettes in Smokers with Mood and Anxiety Disorders, PI: A. Eden Evins, M.D. This study evaluates the effect of progressive nicotine reduction in cigarettes on smoking behavior, toxicant exposure and psychiatric symptoms in smokers with comorbid mood and/or anxiety disorders. Studies of dissemination of clinical best practices for smoking cessation in community health centers.
More information         Click on the picture on the right for more details